PREDICTION OF ENDOPLASMIC RETICULUM RESIDENT PROTEINS USING FRAGMENTED AMINO ACID COMPOSITION AND SUPPORT VECTOR MACHINE

Prediction of endoplasmic reticulum resident proteins using fragmented amino acid composition and support vector machine

Background The endoplasmic reticulum plays an important role in many cellular processes, which includes protein synthesis, folding and post-translational processing of newly synthesized proteins.It is also the site for quality control of misfolded proteins and entry point of extracellular proteins to the secretory pathway.Hence at any given point o

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A simple hypothesis of executive function

Executive function is traditionally conceptualized as a set of abilities required to guide behavior toward goals.Here, an integrated theoretical framework for executive function is developed which has its roots in the notion of hierarchical mental models.Further following Duncan (2010a,b), executive function is construed as a hierarchical Bun recur

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